I’ve spent the past year exploring Guadalajara’s dynamic bar scene—and let me tell you, this city seriously delivers. From moody mezcalerías and natural wine dens to hidden speakeasies and cantinas with real character, there’s something here for every kind of drinker. Since I live in Guadalajara, I’ve had the luxury of lingering in these spots more than once, chatting with bartenders, discovering off-menu gems, and watching how the energy shifts from quiet afternoons to electric nights.
Whether you’re visiting for a few days or live here full-time, this list brings together my favorite cocktail bars, wine spots, and craft beer taprooms across the city’s most vibrant neighborhoods—especially Colonia Americana, Lafayette, and Centro Histórico. These places are more than just bars—they’re where Guadalajara’s creativity, hospitality, and culture really come to life.
Cantinas, Cocktail Bars & Speakeasies
Mecenas Bar in Guadalajara is one of the city’s most impressive new spots, combining a laid-back yet elevated atmosphere with striking design. Tucked away with moody lighting, high ceilings, and bold contemporary art, it feels part cocktail bar, part gallery — ideal for a casual night out or a more memorable evening.
What truly sets Mecenas apart is its meticulous attention to detail. The house-made infusions and liquors are complex and inventive, and the food menu goes far beyond standard bar fare, offering dishes that are just as thoughtfully crafted as the drinks. It’s a must-visit for anyone looking to experience Guadalajara’s creative energy through exceptional cocktails and cuisine.
Cantina de la Ó
📍 Calle Argentina 70, Col Americana
This place is one of the few bars in Guadalajara that opens early, which makes it perfect for an afternoon mezcal and snack. Cantina de la Ó reimagines the classic cantina with a modern flair—vibrant colors, friendly staff, great playlists, and a solid food menu. I’ve dropped in on slow afternoons and also visited during busy weekends—both times, the vibe was spot-on.
Their award-winning birria tacos pair incredibly well with their agave-forward cocktails. They also earned “Best Regional Cuisine” at the 2024 Gastronomic Awards, and Travel + Leisure recently listed them among Mexico’s top dining experiences. Not just a bar—this is a destination.
Habanero Negro
📍 C. Manuel López Cotilla 1228-A, Col Americana
Tucked into a leafy stretch of López Cotilla, Habanero Negro is where I go when I want a fun and lively atmosphere with a cocktail that surprises me. The mixology here is impressive—think smoky mezcal creations with spicy or herbal infusions. Every drink feels thoughtfully designed.
It’s not just about the cocktails, either. Their small plates are excellent, making it a great place for drinks and dinner without committing to a full-on restaurant vibe. The ambiance is spirited.
Farmacia Rita Pérez
📍 C. Colonias, between Vallarta & Pedro Moreno, Col Americana
Housed in a restored 19th-century pharmacy, Farmacia Rita Pérez oozes charm. I love how this space combines vintage apothecary cabinets, moody lighting, and nods to local history—it feels like a time machine with mezcal. The cocktail list leans into herbal and botanical flavors, drawing inspiration from traditional Mexican remedies.
It’s one of the more atmospheric places in the city and a fantastic date spot. Their lavender-infused mezcal cocktail is a personal favorite, and the service is always warm and knowledgeable. They have a nice selection of small plates to order with your cocktails.
El Gallo Altanero
📍 Calle Marsella 126, Lafayette
El Gallo Altanero is a classic for a reason. Their mission is to support independent tequila and mezcal producers, which I really respect—and you can taste the quality in every sip. The staff are passionate about what they pour and love talking agave.
The cantina-style interior is rustic and cozy, and it fills up quickly, especially on weekends. I’ve had many laid-back nights here sipping on their Oaxacan mezcal and snacking on seasonal botanas. It’s the kind of place that always feels like a good idea.
El Gallo Altanero has received amazing accolades from the “World 50 Best Bars” with placing #8 in North America and #48 in the world.
Pare de Sufrir Mezcalería
📍 Calle Libertad 1886, Col Americana
This divey little mezcalería might be my favorite place to drink in Guadalajara. Pare de Sufrir has a grungy, boho vibe—dim lighting, candles, handwritten signs, and excellent mezcal served in clay copitas. It’s raw, authentic, and completely unpretentious.
Don’t come here for service bells and whistles. Come to experience mezcal the way it’s meant to be drunk.
Pimp Speakeasy
📍 Av. de la Paz 2308, Col Americana
As the name suggests, Pimp Speakeasy is over-the-top in the best way. Red velvet, gold accents, dim lighting—it’s theatrical and fun. The cocktail menu is ambitious and leans toward the experimental, which I love.
I’ve come here for both dates and group hangs, and it never disappoints. It’s a little glitzy, a little cheeky, and very Guadalajara.
Cantina La Fuente
📍 Pino Suárez 78, Centro Histórico
For a classic Guadalajara cantina experience, La Fuente is the spot. It’s been open since 1921 and feels like it hasn’t changed much since then—in the best possible way. Expect a worn-in bar top, old-school piano music, and a crowd of loyal locals.
It’s cheap, it’s charming, and it’s essential. I always take first-time visitors here so they can soak up a bit of the city’s old soul.
Wine Bars
El Corcho
📍 Calle Argentina 15, Col Americana
One of my go-to spots when I’m craving wine and good conversation. El Corcho is relaxed and unpretentious, with a rotating selection of wines that pair beautifully with their pizzas and cheese plates.
It’s small, it’s cozy, and you’ll usually find me there mid-week with friends catching up. The staff are happy to walk you through what’s on the list or recommend something new.
Turbio
📍 C. Pedro Moreno 1103, Col Americana
Part retro diner, part wine bar, Turbio is one of the coolest and most versatile spots in the city. Their focus is on natural and low-intervention wines, and their food—think sandwiches, share plates, and bar snacks—is low-key excellent.
It’s perfect for early evenings that might turn into late nights. They also host DJ nights and pop-ups, so there’s often something happening.
Loco Wine
📍 C. Manuel López Cotilla 1235, Col Americana
Located in the heart of Colonia Americana, Loco Wine is a sleek, minimalist space with a serious focus on natural and low-intervention wines. I stumbled across it during a wine-tasting event and quickly became a regular. Their rotating selections often feature lesser-known small producers from Mexico and abroad, offering a fresh take on the wine bar experience.
Their food menu is inspired by Mexican street food which is nicely paired with their wine selections.
Craft Beer & Taprooms
Almacén de Botellas
📍 Av. Miguel Hidalgo y Costilla 1151, Col Americana
Serves food
A fun and casual place to try beers from all over Mexico and beyond. Almacén de Botellas has an impressive bottle selection, rotating drafts, and a crowd that’s always chill.
Great for after-work beers or meeting up with friends before heading elsewhere. I also love their outdoor seating when the weather’s nice.
Loba Gastropub
Loba Gastropub
📍 C. Gregorio Dávila 80, Col Americana
Serves food
Loba is one of Mexico’s best independent breweries, and their Americana taproom is a must for beer lovers. The space is sleek and modern, with great food to match—try the pork belly or tacos.
FAQS
What’s the best neighborhood in Guadalajara for bar hopping?
Colonia Americana is the undisputed hotspot for nightlife in Guadalajara, filled with cocktail bars, wine spots, and taprooms within walking distance. It’s safe, vibrant, and offers something for everyone—from speakeasies to divey cantinas.
Do I need reservations for bars in Guadalajara?
Most bars don’t require reservations, but popular spots like Galgo or Cantina de la Óh can fill up fast on weekends. If you’re visiting with a group or want a prime table, it’s worth calling ahead or messaging on Instagram.
Is it safe to go out drinking in Guadalajara at night?
Generally yes—especially in neighborhoods like Americana, Lafayette, and Providencia, where there’s a strong nightlife scene and good police presence. Still, like any city, stick to well-lit areas, don’t flash valuables, and use apps like Uber or DiDi to get home.
Are bars in Guadalajara LGBTQ+ friendly?
Many of them are! While there are dedicated gay bars in Guadalajara, plenty of mainstream spots—especially in Colonia Americana—are very inclusive and welcome all guests with open arms.
Can I use a credit card at most bars?
Yes, most bars in Guadalajara accept credit and debit cards. That said, smaller cantinas or food stalls attached to bars may still be cash-only, so it’s smart to carry a few pesos just in case.
What time do bars in Guadalajara usually open and close?
Bars generally open around 5–6 PM and stay open until 2–3 AM, especially on weekends. A few like Cantina de la Óh open earlier for day drinking and casual food.
Is there a dress code for bars in Guadalajara?
Most bars are casual, especially in the hipper Americana district. Upscale speakeasies or wine bars may lean smart-casual, but you’ll rarely need formalwear—just aim for stylish and put-together.
Can I find craft beer in Guadalajara?
Absolutely. Guadalajara has a thriving craft beer scene with dedicated taprooms like Insurgente, Loba Gastropub, and Almacén de Botellas pouring Mexican and international brews.
Are bars walkable between each other?
Yes! Especially in Americana and Lafayette, many of the best bars are within a few blocks of each other—perfect for bar hopping on foot. Just wear comfortable shoes and stay aware of your surroundings at night.
Do bars in Guadalajara serve food too?
Many do! From full dinner menus (like at Habanero Negro or Loba Gastropub) to small bites and bar snacks (El Corcho, El Gallo Altanero), you can easily find great food to go with your drinks.
Final Thoughts
Whether you’re sipping a smoky mezcal at a candlelit bar, swirling a pét-nat at a natural wine counter, or enjoying craft beer on a patio with friends, Guadalajara’s bar scene has soul. It’s inventive, warm, and unapologetically Mexican. As someone who lives here, I’ve seen how quickly the city evolves—and these bars are at the heart of that energy.
I’ll be updating this list regularly as new places open and favorites evolve, but for now, consider this your go-to guide for an unforgettable night (or three) out in Guadalajara. ¡Salud!
About the Author
Tim is a seasoned travel writer and the creator of Go Travel Mexico Now, a dedicated resource for travelers exploring Mexico’s vibrant destinations. After relocating to Guadalajara, he has spent years immersing himself in Mexico’s culture, from the iconic beaches of Puerto Vallarta to the nightlife of Mexico City.
With firsthand experience in Mexico’s , Tim has personally visited Tequila frequently and has scoped out of these terrific places.
When he’s not writing, you’ll find him sipping a mezcal cocktail at a bar in Colonia Americana or travel to a new exciting destination in Mexico.
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